Organelles and macromolecular structures are the building blocks of the cells, and are involved in the fundamental processes of life. The scientists in our group investigate the structure of supramolecular assemblies and organelles of intact cells and how they function in health and disease.

Our main approach is through nanomorphomics which attempts to understand the complex 3D array of cells using a diverse array of morphological methods at the molecular resolution of electron microscopy (EM).

Nanomorphomics uses stereology to measure cell structures and cell compartments quantitatively, quantitative immuno-EM to map molecular components and electron tomography to reconstruct 3D structure.